Romain Guyon
Post-doctoral Scientist
After obtaining an MSc in biomedical engineering from Institut National des Sciences Appliquées of Lyon, France (INSA de Lyon) in 2018, I was awarded NDM Prize Studentship at the University of Oxford for a DPhil in Clinical Medicine. Based between the Jenner Institute and the Institute of Biomedical Engineering (IBME), my research focused on the development of delayed vaccine delivery technologies, working with Prof. Anita Milicic, Prof. Eleanor Stride and Prof. Adrian Hill.
During my PhD, I created a microfluidics-based continuous process to produce liquid core-solid PLGA shell microcapsules, engineered to carry a vaccine payload. When co-injected alongside a soluble priming vaccine there core-shell particles release the booster vaccine payload after a tunable time delay, removing the need for additional injections. R21 malaria vaccine was used to demonstrate the ability of the particles to deliver the vaccine with different delays, demonstrating efficacy in a mouse model of malaria. I was awarded the 2023 NDM Graduate Prize for this research.
I am currently a postdoctoral researcher, leading the conceptualisation and development of vaccine delivery technologies within the Milicic group and in collaboration with Prof. Stride at the Institute for Biomedical Engineering. In 2022 I was awarded the Michelson Prize to apply this technology towards the development of encapsulated rabies vaccine for single-injection post-exposure prophylaxis.
Romain Guyon @ Jenner Institute Website
