In a lecture titled:“Shaping Vaccine-Induced Immunity: The Role of Antigen Context, Delivery Route, and Exposure Kinetics”, Anita discussed how antigen context (e.g., choice of adjuvant), kinetics of delivery and the route of immunisation impact innate and adaptive immune responses, ultimately affecting vaccine efficacy. Immune response to vaccination is influenced by a wide range of vaccine- and host-related factors. The talk illustrated using a combination of mouse and human in vitro, ex vivo and in vivo models in investigating early spatio-temporal changes post-vaccination, and the role of local tissue environment. It also highlighted how different vaccination routes generate protective immunity, and how modulating the rate of vaccine administration can impact the response magnitude, immunological recall, and the potential for vaccine dose sparing.